Infinite Unknown

A stroke victim has regained the power of speech after doctors placed a device resembling a teabag filled with stem cells in his brain.

Genetically modified stem cells fitted into a kind of ‘tea bag’ are implanted to the patient’s brain where they are supposed to have an anti-inflammatory effect Photo: EPA

Walter Bast, 49, also regained the use of his right arm after the revolutionary treatment, which prevents brain cells from dying.

If further trials of the treatment are successful, it could be on the market in as little as five years, providing fresh hope for the 45,000 Britons each year who suffer a haemorrhagic stroke, where a blood vessel in the brain bursts.

Currently, the only option is surgery, which has a variable success rate. Half of surgery patients will die within a month and just one in 20 patients will recover to the extent of Mr Bast.

The pioneering treatment, called CellBeads, involves cutting away part of the skull to tie off leaking blood vessels and remove blood from the brain.

Surgeons then insert the 2cm by 2cm ‘teabag’ filled with capsules stuffed with around a million stem cells.

The stem cells, taken from bone marrow, have been genetically engineered to make a drug known as CM1 that protects brain cells from dying. This lets the cells rejuvenate and repair the damage done by the stroke.

After around two weeks, doctors at the International Neuroscience-Institute in Hanover, Germany, removed the ‘teabag’, resulting in Mr Bast regaining his speech and the use of his right arm.

Speaking a week after the operation, the first of its kind in the world, Mr Bast, a mechanic, said: “I feel a lucky guy.”

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Tags: Brain, cells, Health, immune system, Medicine, Neuroscience, Science, stem cells, strokes

Mozart Requiem (KV 626)

(NaturalNews) Music, the universal language of mood, emotion and desire, connects with us through a wide variety of neural systems. Researchers have discovered evidence that music stimulates specific regions of the brain responsible for memory, language and motor control. They have located specific areas of mental activity linked to the emotional responses elicited by music. Now new research conclusions have identified how the affect of music could replicate the effects of hormone replacement therapy in the prevention of Alzheimer’s disease and dementia.

The August 7 issue of Medical Hypotheses reports these conclusions resulting from experience that has shown music to be useful in therapy for neuropsychiatric disorders resulting from both functional and organic origins. However, the mechanisms of the action of music on the brain have remained largely unknown despite an increase in scientific studies on the topic.

The results of past studies have clarified that music influences and affects cranial nerves in humans from fetus to adult. To explain how it works at the cellular level, researchers proposed that the neurogenesis, regeneration and repair of the cerebral nerves are the result of adjustments through the secretion of steroid hormones ultimately leading to cerebral plasticity.

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Tags: Alzheimer, Brain, children, Cortisol, Disease, estrogen, Music, Neurons, Neuroscience, Parkinson, strokes, testosterone

For years, Johnson & Johnson obscured evidence that its popular Ortho Evra birth control patch delivered much more estrogen than standard birth control pills, potentially increasing the risk of blood clots and strokes, according to internal company documents.

But because the Food and Drug Administration approved the patch, the company is arguing in court that it cannot be sued by women who claim that they were injured by the product — even though its old label inaccurately described the amount of estrogen it released.

This legal argument is called pre-emption. After decades of being dismissed by courts, the tactic now appears to be on the verge of success, lawyers for plaintiffs and drug companies say.

The Bush administration has argued strongly in favor of the doctrine, which holds that the F.D.A. is the only agency with enough expertise to regulate drug makers and that its decisions should not be second-guessed by courts. The Supreme Court is to rule on a case next term that could make pre-emption a legal standard for drug cases. The court already ruled in February that many suits against the makers of medical devices like pacemakers are pre-empted.

More than 3,000 women and their families have sued Johnson & Johnson, asserting that users of the Ortho Evra patch suffered heart attacks, strokes and, in 40 cases, death. From 2002 to 2006, the food and drug agency received reports of at least 50 deaths associated with the drug. Continue reading »

Tags: birth control, Bush administration, diabetes, estrogen, FDA, Food and Drug Administration, Health, heartburn, Johnson & Johnson, Ortho Evra, Propulsid, Rezulin, schizophrenia, strokes, Supreme Court, Vioxx, Zyprexa