Scientists have already created large-scale human tissue in a lab using methods like 3D printing, but it’s been much harder to grow the small, delicate blood vessels that are vital to tissue health.
“The main limiting factor for tissue engineering … is the lack of a vascular network,” says study co-author Joshua Gershlak, a graduate student at Worcester Polytechnic Institute (WPI) in Massachusetts, in a video describing the study. “Without that vascular network, you get a lot of tissue death.”
The aims of this study were to clarify the effects of dietary boric acid or borax, as a boron (B) source, on hormonal status (leptin, insulin, triiodothyronine (T3), and thyroxine) and some biochemical parameter levels as glucose, carnitine, nonesterified fatty acids, and betahydroxybutyric acid in rats. A total of 30 Sprague-Dawley male rats were divided into three equal groups: the animals in the first group (control) were fed with a standard rodent diet containing 6.4 mg B/kg, and the animals in the experimental group were fed with a standard rodent diet added with boric acid and borax (100 mg B/kg) throughout the experimental period of 28 days. The B compounds especially borax decreased leptin, insulin, and glucose levels, whereas increased T3 and carnitine levels in plasma. In addition, body weight of rats was found to be low in the boric acid group at the end of 4 weeks. Consequently, our results demonstrate that B supplementation (100 mg/kg) in diet decreases body weight, leptin, and insulin, whereas increases T3 levels in plasma, so enhances the metabolic activity of rats. Between the B compounds used in this study, it was found that borax had a greater effect on hormonal status than boric acid.
A common dietary contaminant, aflatoxin B1 (AFB1), has been shown to be a potent mutagen and carcinogen in humans and many animal species. Since the eradication of AFB1 contamination in agricultural products has been rare, the use of natural or synthetic free radical scavengers could be a potential chemopreventive strategy. Boron compounds like borax (BX) and boric acid are the major components of industry and their antioxidant role has recently been reported. In the present report, we evaluated the capability of BX to inhibit the rate of micronucleus (MN) and sister chromatid exchange (SCE) formations induced by AFB1. There were significant increases (P < 0.05) in both SCE and MN frequencies of cultures treated with AFB1 (3.12 ppm) as compared to controls. However, co-application of BX (1, 2 and 5 ppm) and AFB1 resulted in decreases of SCE and MN rates as compared to the group treated with AFB1 alone. Borax gave 30-50 % protection against AFB1 induced SCEs and MNs. In conclusion, the support of borax was especially useful in aflatoxin-toxicated blood tissue. Thus, the risk on target tissues of AFB1 could be reduced and ensured early recovery from its toxicity.
This study was carried out to evaluate the protective role of borax (BX) on genotoxicity induced by aluminum (Al) in rat liver, using liver micronucleus assay as an indicator of genotoxicity. Sprague-Dawley rats were randomly separated into six groups and each group had four animals. Aluminum chloride (AlCl₃; 5 mg/kg b.w.) and BX (3.25 and 13 mg/kg b.w.) were injected intraperitoneally to rats. Besides, animals were also treated with Al for 4 consecutive days followed by BX for 10 days. Rats were anesthetized after Al and BX injections and the hepatocytes were isolated for counting the number of micronucleated hepatocytes (MNHEPs). AlCl₃ was found to significantly (p < 0.05) increase the number of MNHEPs. Rats treated with BX, however, showed no increase in MNHEPs. Moreover, simultaneous treatments with BX significantly modulated the genotoxic effects of AlCl₃ in rats. It can be concluded that BX has beneficial influences and has the ability to antagonize Al toxicity.
Aluminum; borax; in vivo; liver; micronucleus assay; rat
“At last. But taking into account they are now part of the former manufacturer of Zyklon B, Messrs I.G.Farben, whose plant was specifically excluded from Allied Bomber attacks in WWll on instructions from the Rothschilds and others, do we really think Monsatan will be given any real conviction?”
Beginning in 2003, software engineer William Connolley quietly removed the highly inconvenient references to the global cooling scare of the 1970s from Wikipedia, the world’s most influential and accessed informational source.
It had to be done. Too many skeptics were (correctly) pointing out that the scientific “consensus” during the 1960s and 1970s was that the Earth had been cooling for decades, and that nascent theorizing regarding the potential for a CO2-induced global warming were still questionable and uncertain. Continue reading »
Only Slightly Less Sea Ice Now Than Little Ice Age
In a new paper (Stein et al., 2017), scientists find that Arctic sea ice retreat and advance is modulated by variations in solar activity.
In addition, the sea ice cover during the last century has only slightly retreated from the extent reached during coldest centuries of the Little Ice Age (1600s to 1800s AD), which had the highest sea ice cover of the last 10,000 years and flirted with excursions into year-round sea ice.
The Medieval Warm Period sea ice record (~900 to 1200 AD) had the lowest coverage since the Roman era ~2,000 years ago.
“So what does he recommend we do? He suggests drinking water, the very elemental material the light activates, which gives us not only hydration but energy. He then cites green juices as a great source of H3O2, because plant cells have already turned H2O into H3O2. Therefore we don’t have to wait for our body to make this transformation. Dr. Pollack has already studied turmeric and coconut and documented their energizing effects, which he will share in forthcoming papers.And he suspects that many foods have H3O2 water inside them noting the more we eat those foods, the more H3O2 water we ingest, the higher our energy goes.”
Are we, too, solar powered, like plants? It’s no longer a question, it’s an answer.
Summary of TEDxtalk: Water, Cells, Life by Dr. Gerald Pollack, a water scientist at the University of Washington, tell us where the energy comes from that supplies our bodies with get up and go. In it, Dr. Pollack challenges the long-held explanation that the bulk of our energy comes from food, in the form of calories. He provides an entirely new and very exciting paradigm, one that will open up new dimensions of body energy for accelerated healing and vitality. And he shares his unexpected laboratory results to back his explanation up. This will surely be a seminal TEDxtalk.
In it Dr. Pollack makes two unexpected and paradigm-advancing points. Hold onto your hat.
The first point is that there is a new form of water, H3O2. Just give yourself a sec to take that in. The news of a new form or phase of water is really starting to circulate. The old paradigm of vapor, liquid, ice has been facing theoretical challenges for at least a 100 years, but the three-phase paradigm remained a convenient knowledge package, given the complexities and doggedly unexplained mysteries of water behavior. Don’t you love that water has unexplained behavior? Water scientists always speculated that water exists on a spectrum, but where they drew the boundary lines was more arbitrary than we first understood, and they actually missed one elementally important phase.
Water comes not only as vapor, liquid, ice, but between liquid and ice, there is a phase, a form, that can most easily be recognized as gel. It’s full of microscopic crystals, like snowflakes, but not yet, like ice, frozen in place. It’s a shifting form called liquid crystalline, sometimes called structured, or ordered water. It has the malleability of crocheted lace, or a mesh sack. Granted, this phase of water is hard to spot as it takes place on a molecular, even a nanoparticle, level. This science is so new a name hasn’t yet been settled on and scientists from Russia to Korea, to Italy, to the US are chasing the implications and meeting at the intersection of biology, chemistry and quantum physics. It takes all those disciplines and maybe more to try to explain water. Continue reading »
“The principles of nano-particle smart dust geo engineering has been highlighted by Dane Wiginton for years, but, as time advances, the technology does too, highlighting the probability of our exposure to ever more destructive clouds.
Time to buy breathing masks….the Japanese wear them openly.
Smart dust is a name given to extremely small computing particles, RFID chips, or other very small technologies.
A popular article from Extreme Tech describes it in the headline: “Smart dust: A complete computer that’s smaller than a grain of sand.” An article from War is Boring is titled “Future Military Sensors Could Be Tiny Specks of ‘Smart Dust’ New technologies allow for extremely small—and ubiquitous—military sensors.” A paper from University of California, San Diego describes smart dust:
“The term “smart dust” originally referred to miniature wireless semiconductor devices made using fabrication techniques derived from the microelectronics industry. These devices incorporate sensing, computing and communications in a centimetre-sized package.”
It is promoted as an eventuality, that smart dust will cover streets and buildings to identify people, that people will have smart dust in their bodies, and other things in mainstream television and media. They paint a utopian, blissful picture of it.
A recently-retired top scientist from the America’s National Oceanic and Atmospheric Administration (NOAA) has accused his superiors of fudging data to hide a slowdown in the rise of global temperatures ahead of the UN Climate Change Conference in 2015.
John Bates told the Sunday Mail that Thomas Karl, the head of the climate change department at the government agency, authored a paper based on false data, “rushed” it into publication, and then saw his work used to make international commitments to fight global warming worth hundreds of billions of dollars.
After rising by 0.113C per decade between 1950 and 1999, temperatures appeared to have stabilized between 2000 and 2014, despite rising levels of CO2 emissions, which climate change scientists said were responsible for the earlier warming.
The “pause,” unveiled in a 2012 UN report, shook up the entire scientific community, and cast doubt upon hundreds of models confidently predicting a trend of accelerating warming.
But then, Karl’s “pausebuster”paper emerged, just month before Barack Obama, Angela Merkel and scores of other world leaders congregated in Paris, showing that global warming was not slowing down, but actually accelerating to 0.116C per decade.
Telomeres, repeating sequences of DNA located at the ends of chromosomes, play a key role in survival and aging. Preserving the length of telomeres has been shown to extend cell lifespan, and many researchers now believe that protecting telomere length holds the key to slowing down the aging process – and sustaining the beneficial qualities of a youthful life.
We can age gracefully with the power of nutrition. There is plenty of scientific evidence that a healthy diet coupled with high-quality supplements can help to maintain our telomere length. Keep reading to see how four common vitamins can reverse the unwanted shortening of telomeres – and prevent the negative effects of aging. Continue reading »